Information About How Methotrexate Injections Work

Methotrexate is one of the most special, strongest and potentially dangerous drugs, which is why this drug is only diagnosed on special cases of breast cancer, leukemia, rheumatoid arthritis, psoriasis, osteosarcoma, and extremely dangerous neoplastic diseases that are potentially or definitely cancerous.

Classified as an anti-metabolite, the drug works by obstructing regular synthesis of DNA and cell production, and cancer cells, the bone marrow and the urinary tract are found to be more sensitive to the effects of Methotrexate. When the growth and production of malignant cells are faster than normal cells, Methotrexate can then be prescribed without giving permanent and severe damage to the healthy cells. The medicine can help control your sickness and the symptoms but will not really work on treating any disease.

Methotrexate is given in injection form and straight to a vein or muscle and even into the spinal cord, depending on where it will give the most benefits. High doses of injections are sometimes prescribed for osteosarcoma, a kind of bone cancer, and other neoplastic diseases. Methotrexate cannot be just taken anytime, for it can be fatal to fetuses, people with a history of allergic reactions to medicines, and those who have diseases other than what Methotrexate is prescribed for.

A few known Methotrexate side effects include diarrhea, thinning or weak hair, skin allergies, acne, loss of appetite, mouth sores, bloody urine and/or stool, stomach ulcers, cirrhosis of the liver, and most commonly low white blood cell count, which leads to a weaker immune system and therefore a greater risk of contracting fatigue, fever, nausea, and even pulmonary fibrosis, the growth of fibrous tissues in the lungs. Methotrexate can even cause the formation of malignant lymphoma, a cancer of the lymphatic cells in the immune system.

Taking Methotrexate injections should only be done with the approval of your doctor. Sometimes the patient is taught how to administer the injections on him or herself, but careful attention must be given not to risk an overdose. As with other strong drugs like a high Coumadin or Lisinopril dosage, Methotrexate can be fatal when given in large doses. Taking of other medicines should also be avoided, since Methotrexate can react adversely with other drugs, even those considered generally safe to take like painkillers and antibiotics. To stay as safe as possible when taking Methotrexate, all of your doctor’s advices should be followed, and schedules for appointments and check ups must be adhered to.

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